Lion's Mane Mushroom

Key points

• Lion's mane contains hericenones and erinacines — compounds that cross the blood-brain barrier and stimulate NGF synthesis
• NGF (Nerve Growth Factor) promotes the growth and maintenance of neurons — relevant for learning, memory, and neuroplasticity
• Studies in mild cognitive impairment show meaningful improvement over 16 weeks; benefits reverse when stopped
• Best taken in the morning — some users report mild stimulation; not ideal for evening use
• 500–1000mg of standardised extract daily is the studied range; whole mushroom powder has lower active compound content