Glucosamine + Chondroitin + MSM

Key points

• Glucosamine is a precursor to glycosaminoglycans — the primary component of cartilage
• Chondroitin attracts water into cartilage, maintaining thickness and shock absorption
• MSM (methylsulfonylmethane) reduces inflammation and oxidative stress in joint tissue
• Best evidence is for knee osteoarthritis — consistent use over 3–6 months shows benefit
• Works best alongside collagen — they operate on different layers of joint structure